Use Shift-Windows Key-S and Snip & Sketch
After many years of using Snagit (see below), this has become my primary screenshot method. Hit the Shift-Windows Key-S keyboard combo, and you have a choice of shooting the full screen, a rectangular selection, a freehand selection, or an individual program window. An alternative way to invoke Snip & Sketch is via the Action Center’s Screen snip button.
After hitting this keyboard shortcut, you momentarily see a small thumbnail panel notification at lower right that says Snip Saved to Clipboard. Tap this to open the Snip & Sketch window. In this, you can mark up the image with a pen, pencil, highlighter, eraser, ruler, and cropping tool. Then you can save the image to a folder of your choice, or share it using the standard Windows Share menu. That lets you send the image to Instagram, Messenger, Mail, or any other app that accepts the file type. It also lets you send it to a nearby PC with Nearby Sharing enabled.
A couple things I wish Snip & Sketch had are text overlay and basic shapes, including the ever-useful arrow. If you only want to use this tool, you can go into Windows’ Settings app and choose Ease of Access > Keyboard and choose Use the PrtSc Button to Open Screen Snipping. Note that this requires restarting Windows.